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Revealing the Invisible To Create a Better and Healthier World.

Revealing the Invisible To Create a Better and Healthier World.

Revealing the Invisible To Create a Better and Healthier World.

Leica Microsystems is a market leader in microscopy, offering instruments ranging from stereo to digital microscopy and super-resolution. We provide sample preparation solutions for electron microscopy. Leica users span various fields, including life science research, manufacturing, surgery, and education.

The Relevance of Our Work: Impacting Sectors for a Better, Sustainable World

Medical Microscopy

With a portfolio covering microsurgery disciplines including ophthalmology, neurosurgery, otolaryngology (ENT), plastic reconstructive surgery and dentistry, there is a surgical microscope from Leica to meet your needs.

Life Science Research

Leica Microsystems’ life science research microscopes support the imaging needs of the scientific community with advanced innovation and technical expertise for the visualization, measurement and analysis of microstructures.


Industrial Applications

Maximizing uptime and achieving targets efficiently help your bottom line. Leica microscope solutions can give you insights into the smallest sample details as well as analyze, document, and report results fast and reliably.

Our Latest Articles

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The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments.

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An 8-color spectral unmixing result from a hyperspectral SRS (stimulated Raman scattering) dataset, showing the biochemically distinct structures of a fresh, untreated apple slice.

How to Prepare Samples for Stimulated Raman Scattering (SRS) imaging

Find here guidelines for how to prepare samples for stimulated Raman scattering (SRS), acquire images, analyze data, and develop suitable workflows. SRS spectroscopic imaging is also known as SRS…

RPE65 Gene Therapy Subretinal Injection: Benefits of Intraoperative OCT

Discover how RPE65 gene therapy subretinal injection procedures in patients with Leber congenital amaurosis is supported by intraoperative Optical Coherence Tomography.

Accelerating Discovery for Multiplexed Imaging of Diverse Tissues

Explore IBEX: Open-source multiplexed imaging. Join the collaborative IBEX Imaging Community for optimized tissue processing, antibody selection, and human atlas construction.
Particulate contamination in between moving metal plates.

Key Factors for Efficient Cleanliness Analysis

An overview of the key factors necessary for technical cleanliness and efficient cleanliness analysis concerning automotive and electronics manufacturing and production is provided in this article.
Microscope equipped with a K7 color CMOS camera for life-science and industry imaging applications.

Technical Terms for Digital Microscope Cameras and Image Analysis

Learn more about the basic principles behind digital microscope camera technologies, how digital cameras work, and take advantage of a reference list of technical terms from this article.
Images of the same area of a processed wafer taken with standard (left) and oblique (right) brightfield illumination using a Leica compound microscope. The defect on the wafer surface is clearly more visible with oblique illumination.

Rapid Semiconductor Inspection with Microscope Contrast Methods

Semiconductor inspection for QC of materials like wafers can be challenging. Microscope solutions that offer several contrast methods enable fast and reliable defect detection and efficient workflows.

Transforming Multiplexed 2D Data into Spatial Insights Guided by AI

Aivia 13 handles large 2D images and enables researchers to obtain deep insights into microenvironment surrounding their phenotypes with millions of detected objects and automatic clustering up to 30…
Applying dispersive viscoelastic to coat the anterior chamber. Image courtesy of Arsham Sheybani, MD, Washington University School of Medicine.

Dislocated Cataract Angle Closure Aided by Intraoperative OCT

Learn how a dislocated cataract was treated with angle closure assisted by intraoperative OCT to achieve long-term good results without future lens dislocation.
Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.

Notable AI-based Solutions for Phenotypic Drug Screening

Learn about notable optical microscope solutions for phenotypic drug screening using 3D-cell culture, both planning and execution, from this free, on-demand webinar.
Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin.

Understanding Tumor Heterogeneity with Protein Marker Imaging

Explore tumor heterogeneity and immune cell dynamics. See how quantitative imaging analysis reveals spatial relationships and molecular insights crucial for advancing cancer research and therapeutics.

The Best Team Wins

Diversity, Equity & Inclusion

We strive to continuously improve and sustain an inclusive culture in which diversity provides deeper customer insights and creates a competitive advantage in the markets we serve. By attracting, developing and retaining the best team of diverse, engaged and empowered employees, we help realize life's potential for ourselves, our customers and our shareholders.

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Evolved ARveo 8 surgical microscope leads to clinical value creation for 3D brain-tumor visualization and enables freedom of movement with a surgical…

Next-generation Integrated Intraoperative OCT for Proveo 8 to be Unveiled at the FLORetina ICOOR Meeting 2023

Dimensionality Reduction (UMAP)

The latest release of Aivia AI Image Analysis Software offers accurate multiplex cell detection and automatic clustering with up to 30 markers

Image caption: A panel of approximately 30 biomarkers targeted towards various leukocyte lineages, epithelial, stromal, and endothelial cell types was utilized to characterize the tumor microenvironment in human colon adenocarcinoma (CAC) tissue. Image shown displays multiple markers including PANCK, EPCAM, NaK, Vimentin, Ki67, SURV, and DAPI.

Live Webinar - Wednesday, November 8, 2023, 8:00 AM (PST)

Join us in this webinar to learn more about how the convergence of technology and…

The extended site is set to deliver innovations in surgical microscopes and to double production of Leica Microsystems’ microscopes for surgical and…

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